diff --git a/lib/datasource/pypi.js b/lib/datasource/pypi.js
index 77819b6622ed74d0ed6fee6ca7705ada35949e85..0493eddfd87f49d3d4ae7c2700b8ec219dc5eb27 100644
--- a/lib/datasource/pypi.js
+++ b/lib/datasource/pypi.js
@@ -8,7 +8,7 @@ module.exports = {
 };
 
 function normalizeName(input) {
-  return input.toLowerCase().replace(/-/g, '_');
+  return input.toLowerCase().replace(/(-|\.)/g, '_');
 }
 
 async function getPkgReleases(purl, config = {}) {